How Long Does CBD Stay in a Dog’s System?

How Long Does CBD Stay in a Dog’s System?

February 22, 2024

The duration that CBD remains in a dog’s system varies, but on average, it can be detected for about 24 to 72 hours after administration. This timeframe, however, is influenced by several factors, including the dosage, frequency of use, the dog’s metabolism, and the form of CBD product used. Understanding these aspects can help pet owners and veterinarians make informed decisions about incorporating CBD into a dog’s wellness routine, especially considering its growing popularity for managing anxiety, pain, and other conditions in pets.

The Science of CBD in Dogs

Cannabidiol (CBD) is a compound found in cannabis and hemp plants. Unlike tetrahydrocannabinol (THC), the primary psychoactive ingredient in marijuana, CBD does not produce a “high” but has been studied for its potential therapeutic effects, including anti-inflammatory, analgesic, and anti-anxiety properties. When administered to dogs, CBD is absorbed into the bloodstream, interacts with the endocannabinoid system (ECS), and is eventually metabolized by the liver before being excreted.

Factors Affecting CBD Retention

1. Dosage

The amount of CBD administered plays a significant role in how long it stays in a dog’s system. Higher doses are likely to remain detectable for a longer period as the body takes more time to metabolize and eliminate the compound.

2. Frequency of Use

Regular use of CBD can lead to accumulation in the body, extending the detection window. For dogs receiving CBD as a daily supplement, the compound may be present in their systems for a longer duration compared to those receiving it sporadically.

3. Metabolism

Just like humans, dogs have varying metabolic rates, which can influence how quickly CBD is processed and eliminated. Factors such as age, activity level, and overall health play a crucial role in a dog’s metabolism. Younger, more active dogs may metabolize CBD faster than older, less active ones.

4. Product Type

The form in which CBD is administered (e.g., oil, treat, capsule) affects its bioavailability and, consequently, how long it remains detectable in the system. CBD oils, for example, are generally absorbed and metabolized differently than edibles or topical products, potentially influencing the duration of their effects.

5. Individual Differences

Individual physiological differences among dogs, such as weight, diet, and genetic factors, also impact CBD metabolism. These variations mean that the persistence of CBD in the system can differ significantly from one dog to another, even when given the same dosage under similar conditions.

CBD Metabolism in Dogs

After administration, CBD is absorbed into the bloodstream and transported throughout the body, where it interacts with cannabinoid receptors as part of the ECS. The liver then metabolizes CBD, breaking it down into metabolites that can be more easily excreted from the body through urine and feces. The process involves various enzymes, primarily from the cytochrome P450 family, which can be affected by the aforementioned factors, altering the speed of CBD metabolism.

Detection of CBD in Dogs

While the average timeframe for CBD to stay in a dog’s system is 24 to 72 hours, detecting the compound can depend on the type of test used. Most standard drug screenings for pets are not designed to detect CBD specifically but may look for THC and other cannabinoids. Given that some CBD products contain trace amounts of THC (especially those derived from marijuana rather than hemp), understanding the product’s composition is crucial for anticipating potential test outcomes.

Considerations for Use

Given the variability in how long CBD can stay in a dog’s system, pet owners considering CBD for their dogs should consult with a veterinarian, especially if the pet is taking other medications. CBD can affect the metabolism of other drugs, potentially leading to adverse effects. A vet can provide guidance on appropriate dosing and monitoring to ensure the safe and effective use of CBD.


In summary, CBD can remain in a dog’s system for 24 to 72 hours, but this is influenced by factors like dosage, frequency of use, the dog’s metabolism, product type, and individual physiological differences. As research into the benefits and pharmacokinetics of CBD in dogs continues to evolve, pet owners are advised to proceed with caution and seek professional advice when considering CBD for their pets. With proper guidance, CBD can be a valuable addition to a dog’s wellness regimen, offering potential relief for a variety of conditions.